Endocrine Abstracts

Introduction: Autophagy is a major clearance mechanism that destroys organelles and damaged proteins to keep cellular survival and homeostasis. Previous experimental studies have showed that autophagy has crucial role in the progression of diabetes and kidney diseases.Aim: This pilot cross-sectional study aimed to investigate the association between serum concentrations of beclin-1, a key regulator of autophagy, and diabetic nephropathy.<p class="abs...

Introduction: The contribution of chronic hepatitis C virus (HCV) infection per se in thyroid autoimmunity and dysfunction remains controversial.Aim: To investigate the prevalence of thyroid disorders and the possible association between thyroid dysfunction and different factors in a cohort of HCV untreated patients.Material and methods: A total 1050 patients with untreated HCV infection were enrolled in this study. Thyroid functio...

Background: Irisin is a new myokin and adipokine related to human obesity and insulin resistance status.Aim: To assess serum irisin level as well as to investigate whether serum irisin is related to glycemic indicators, and micro and macrovascular complications in patients with T2DM.Methods: The study included 60 T2DM patients and 30 healthy controls. Anthropometric measures, neurological assessment and fundus examination were done...